Background: Patients with high-risk NSTE ACS managed with an early invasive strategy often require CABG for revascularization.The clinical outcomes among this cohort are not well characterized, so we analyzed CABG procedures using SYNERGY data.

Methods: A total of 1793/9902 (18.1%) patients underwent post-randomization CABG without preceding PCI. Clinical endpoints were death or MI by 6 months, in-hospital bleeding。 As exploratory analyses are unadjusted for potential differences between treatment groups and post-randomization confounders.

Results: The median time to CABG from randomization was 90.5 (44.5-166.6) hours. Patients undergoing CABG experienced a substantial risk of clinical events regardless of treatment assignment. See table.

Conclusion: Despite advances in percutaneous revascularization, a sizable proportion of high-risk ACS patients require CABG.Among these patients, CABG is associated with a substantial burden of death or MI and major bleeding events. Unadjusted ischemic and bleeding outcomes following initial treatment with enoxaparin appear to be similar to those observed with UFH.

急性冠状综合征病人需要冠状动脉造影分流术的临床结果—来源于Synergy 临床。